Mechanobiological response of articular cartilage subjected to simultaneous compression and sliding

Simultaneous Magnetic Resonance Imaging and Consolidation Measurement of Articular Cartilage

Magnetic resonance imaging (MRI) offers the opportunity to study biological tissues and processes in a non-disruptive manner. The technique shows promise for the study of the load-bearing performance (consolidation) of articular cartilage and changes in articular cartilage accompanying osteoarthritis. Consolidation of articular cartilage involves the recording of two transient characteristics: ...

An In-Vitro Investigation of Sliding Friction Between Biomaterials for Cartilage Substitution and Articular Cartilage

Understanding friction and wear of biomaterials when in contact with articular cartilage is vital within the development of future hemi-arthroplasty and cartilage substitution. This study aimed to compare the frictional properties of single phase and biphasic polymeric materials against articular cartilage. Continuous sliding friction was applied by means of a simple geometry wear simulator. Th...

Multiscale Analysis of Tendon Subjected to Shear and Compression Demonstrates Strain Attenuation, Uncrimping, and Sliding

Injurious mechanical compression of bovine articular cartilage induces chondrocyte apoptosis.

A bovine cartilage explant system was used to evaluate the effects of injurious compression on chondrocyte apoptosis and matrix biochemical and biomechanical properties within intact cartilage. Disks of newborn bovine articular cartilage were compressed in vitro to various peak stress levels and chondrocyte apoptotic cell death, tissue biomechanical properties, tissue swelling, glycosaminoglyca...

Depth-dependent Relaxation of Articular Cartilage in Unconfined Compression

INTRODUCTION Articular cartilage (AC) is an inhomogeneous, anisotropic and multiphasic composite. Depth-dependent strain distribution in full thickness AC has previously been investigated with optical methods (Guilak, 1995; Schinagl, 1997; Wang, 2003). Depth and time-dependent compressive strain has been predicted with theoretical models (Li, 2000; Wang, 2001). Most recently, Electronic Speckle...